A blood clotting factor mutation is known as Factor V Leiden. Your risk of getting abnormal blood clots, which most frequently occur in the legs or lungs, can increase due to this mutation.
In the majority of Factor V Leiden patients, abnormal clots never form. However, in those who do, these abnormal clots can cause long-term health issues or even pose a threat to life.
Symptoms
There are no symptoms associated with the factor V Leiden mutation itself. The emergence of an atypical blood clot could be the first sign that you have factor V Leiden because the condition increases your chance of getting blood clots in the leg or lungs.
Some clots don’t do any harm and vanish on their own. Others may pose a threat to life. Blood clot symptoms vary depending on what portion of your body is afflicted.
A clot In a deep vein
Deep vein thrombosis (DVT), which most frequently affects the legs, is what causes this. DVT symptoms might not always manifest. If symptoms do materialise, they may include:
Pain
Swelling
Redness
Warmth
A clot that travels to your lungs
When a piece of a DVT escapes and goes through the right side of your heart to your lung, blocking blood flow, this condition is known as a pulmonary embolism. Life may be in danger in this circumstance. Some warning signs and symptoms include:
sudden breathlessness
breathing in causes chest pain
a cough that exhales sputum that is red or has blood in it
a quick heartbeat
Causes
If you have factor V Leiden, you either inherited one copy of the flawed gene or, in rare cases, two copies. Your risk of getting blood clots increases slightly if you inherit one copy. Your risk of getting blood clots significantly rises if you inherit two copies, one from each parent.
Pathophysiology
A single-point mutation in the factor V gene (guanine to adenine at nucleotide 1691) results in factor V Leiden, which causes glutamine to replace arginine at amino acid 506. In factor V and factor Va, this eliminates the Arg506 cleavage site for activated protein C. The results are an increase in factor Va’s procoagulant activity and a decrease in factor V’s anticoagulant activity.
Diagnosis
if you have a strong family history of abnormal blood clots or if you have experienced one or more episodes of abnormal blood clotting. A blood test by your doctor can determine whether you have factor V Leiden.
Treatment
In order to treat patients who experience atypical blood clots, doctors typically administer blood-thinning drugs. Typically, those with the factor V Leiden mutation who have not yet developed abnormal blood clots do not require this type of medication.
If you have the factor V Leiden mutation and are having surgery, your doctor may advise you to take additional precautions to avoid blood clots. These safety measures could include:
a brief blood thinner regimen
Inflatable leg wraps that collapse and inflate to keep your legs’ blood flowing
compression hose
exercising shortly after surgery
Prognosis
Most persons with this disease never have pregnancy difficulties or blood clots. But you should discuss what to anticipate in your specific circumstance with your provider.
Does factor V Leiden have an impact on lifespan?
The majority of people’s life expectancies are unaffected by Factor V Leiden. Prompt treatment can avoid a fatal outcome even if you acquire a blood clot. Any worries you have regarding your prognosis or potential problems should be brought up with your doctor.
Complications
Blood clots in the legs (deep vein thrombosis) and lungs (pulmonary embolism) can be brought on by factor V Leiden. These blood clots may endanger life.
Factor V Leiden in Ayurveda
We can prevent the extent of clot formation by Ayurveda therapies, lifestyle, and diet. The preventive method is more relevant in Factor V Leiden and Ayurveda has a strong hold in this area. Please talk to a qualified Ayurveda Doctor and get a plan regarding lifestyle and food.
Management of Factor V Leiden with Ayurveda
Description
It is the abrupt loss of function in a specific brain region. Paralysis, as the name implies, typically results in difficulty moving an arm or leg. The person’s feelings might be impacted.
Symptoms
Swelling
Pain
Tenderness
Redness
Warm sensation
Causes
It is believed that a blood artery in the brain has contracted as a result. Risk factors include smoking, diabetes, obesity, arterial hardening, high blood pressure, and family history. Such a situation is attributed in the Ayurvedic classics to a restriction of Vata movement. The two types are hemorrhagic (when a weak blood artery supplying the brain breaks) and ischaemic (where the blood supply is cut off due to a blood clot).
Samprapti
Factor V Leiden develops as a sickness, and
Displays as the pathogenesis progresses the following actions in that order –
Pitta that has been worsened by the aforementioned factors exits its sites and enters the blood.
Being a mala (waste product) of rakta, the pitta achieves a quantitative increase when mixed with rakta.
The rakta is vitiated by the pitta. The drava dhatu, or liquid part (fluid), of other tissues like mamsa (muscles), meda (fat), etc. pours out of their respective tissues and mixes with rakta as a result of the heat of Pitta.
This increases the amount of rakta over and beyond what is typically present.
Blood starts to leak through numerous body holes because of the pressure of the blood and the heat of pitta, which damages the blood vessel walls.
The mouth, nose, ears, eyes, skin, anus, penis, and vagina can all bleed.
It refers to the vitiated blood that is leaking through the body’s orifices.
Treatment plan
The type of Factor V Leiden you have, along with the afflicted area of the brain and the underlying cause, will determine your course of treatment. Treatments should aim to lower cholesterol levels, lower blood pressure, and prevent and dissolve blood clots. A patient who has experienced stroke-related paralysis for more than a year needs more intensive care. This occurs because the muscles in an area of the body that has been inactive for a long time begin to deteriorate.
Samana chikitsa
Snehana, Swedana, and Virechana are examples of internal and external therapy. Medication can boost general immunity as well as muscle strength.
Sodhana chikista
Dhanwantharam Kashayam
Dhanwantharam Tailam
Ksheerabala Tailam
Gorochandai Gulika
Hinguvachadi Gulika
Vaiswanara Churna
Gotukola capsules
Arjuna capsules
Chandraprabha vati
Curcumin capsules
Lodhrasava
Usheerasava
Pravala pisti
Shatamulyadi lauh
Home remedies
Garlic
Brahmi
Tulsi
Turmeric
Neem
Dhamasa
AAHAR’S DIET RECOMMENDATIONS
Include herbs with potent anti-inflammatory, blood-thinning, and anti-microbial properties, such as garlic, ginger, and turmeric, in your diet.
Take in a lot of water.
Avoid foods that are very salty, fried, sour, or oily.
CHANGES IN LIFESTYLE (VIHAR)
In order to manage the illness, Ayurveda recommends a mix of dietary, lifestyle, and herbal adjustments. Under the Hridya Mahakashaya, or the class of herbs specifically for cardiac health, Charaka listed ten medications.
Regular exercise promotes healthy blood vessel function and proper blood circulation.
When travelling for a long time, try to stretch your legs and take a short walk.
Elastic stockings improve blood flow.
Avert extended inactivity
Patients who are confined to beds should routinely perform stretches
In your sleep, try to elevate the leg.
Yoga
Uddiyana Bandha
Upward Abdominal Lock, or Uddiyana Bandha. Completely exhale while holding the breath, bring your stomach in towards your spine, twist your pubic bone towards your navel, and squeeze your sitting bones together. Hold for five to ten seconds, then repeatedly do this. This relieves pressure on the sciatic nerve and the hamstrings.
Stretching your legs in Uttanasana (Standing Forward Bend) and Virabhadrasana I (Warrior Pose I) will assist prevent DVT from reaching your location.
The Food and Drug Administration, United States has not evaluated these statements. This product is not intended to diagnose, treat, cure or prevent any disease. Please consult your GP before the intake.
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