THIKTHAKAM GHRUTHAM -Benefits, Ingredients, Indications, Dosage, Usage, Preparation, Side effects, Equivalent Medicines, Research Papers

Thikthakam ghrutham is an Ayurvedic medicine for skin diseases and improving complexion. It also helps to treat many digestive disorders and beneficial in some psychiatric conditions too.

Benefits of Thikthakam ghrutham

The formulation of Thiktakam is explained as a ghrita yoga in Ashtangahrudayam Kushthachikithsa but it is also used as a kashayam.

Thiktakam Ghee combination is used either as acchasnehapana as a preparatory procedure to Ayurvedic Panchakarma (cleansing therapy) or as samanasneha in small doses after having Kashaya or other rookshana medicines for a while.It helps to  regain health after the rookshan a(drying up ) therapies.

It is very effective in chronic skin diseases like psoriasis, eczema, and atopic dermatitis.

It is found beneficial in healing diabetic wounds and gangrene. Also, fistulae, cervical lymphadenitis, abcesses, oedema, and sinus wounds.

Thiktakam being pacifying Pitta dosha, it is used in many diseases where Agni is deranged. It includes many liver disorders like Obstructive and infective jaundice, hepatitis, liver cirrhosis, and non-alcoholic fatty liver.

In psychiatric disorders where Pitta is the main vitiated Dosha, thiktakam is very much yielding. It is used successfully in Maniac stage of Bipolar disorder, schizophrenia with grandeur or paranoid delusions etc

In some stages of epilepsy also it is found useful.

Kids with some types of Learning disorders and Attention Deficit Hyperactivity Disorder show much affinity to Thiktakam ghritam and it is very beneficial in such conditions. 

Indications of Thikhtakam ghrutham

Pittakushtha      – Skin diseases where redness, raised temperature and burning sensation are   evident.

Pareesarpa        – Herpes

Pitika                   -Boils

Daaha                 -Burning sensation

Thrit                    -Excess thirst

Bhrama              -Giddiness

Kandu                 -Pruritis

Pandwamaya    -Anaemic disorders

Gandamala        – Scrofula/Cervical tubercular lymphadenitis

Dushtavrana      -Non-healing wounds and ulcers

Naadeevrana    -Sinus

Apachi                -Cervical lymphadenitis/Goitre

Visphota             -Skin rash with infected blisters and pustules

Vidradhi             -Abscess

Gulma                 -Indigestion with abdominal pain and distension.

Sopha                 -Oedema

Unmada             -Psychotic conditions

Mada                  -Intoxication

Hridroga             – Chest pain and discomforts, diseases of the heart

Timira                 -Eye diseases including cataract

Vyanga               -Melasma

Grahani              -Irritable bowel syndrome and Malabsorption

Switra                 -Vitiligo

Kamila                 -Jaundice

Bhagandara       -Anal fistulae

Apasmara          -Epilepsy

Udaram                            -Ascites

Pradaram           -Leucorrhoea

Garam                -Chronic and slow poisoning

Arsas                   -Piles

Asrapitta            -Bleeding disorders

And other severe Paittika diseases

Ingredients of Thikthakam ghrutham

Pointed gourdPatolaTrichosanthes dioica Roxb.

It has ant-diabetic, hepato-protective, anti-inflammatory, anti-bacterial, anti-fungal, and wound-healing properties. It has anti-oxidants. It is useful in lowering cholesterol and skin diseases. It acts as a laxative.

Margosa, NeemNimbaAzadirachta indica A. JUSS.  

The important health benefits of this drug include its ability to treat dandruff, soothe irritation, protect the skin, boost the immune system, and reduce inflammation. It also speeds up wound healing, treats gastric conditions, slows the aging process, improves hair and scalp health, maintains sexual organ health, has anti-cancer potential, and helps treat diabetes.

Yellow gentian, HelleboreKaturohiniPicrorhiza kurroa

It is used for Dyspepsia, fever and in purgatives. Although it shows anti-oxidant, anti-inflammatory, and immunomodulatory activities, it is most valued for its hepatoprotective effect. 

Indian barberry/chutro/tree turmericDarviBerberis aristata

It has anti-bacterial, anti-fungal anti-diarrhoeal and anti-cancerous properties. It is used in the treatment of ophthalmic infections.

false pareira root/ velvet leafPaathaCissampelos pareira L.

It has anti-inflammatory and antiseptic actions. This plant is used to treat gynaecological conditions. Patha is used in the treatment of chronic non-healing ulcers and sinuses. It is also used in the treatment of chronic skin diseases and in the treatment of poisonous bites.

Stinging nettleDuralabhaTragia involucrata Linn.

This plant is used in many conditions like wounds, eczema, scabies and other skin infections. It has anti-inflammatory property. It is used to treat piles, migraine, warts and rheumatism.

Small-flowered fumitoryParpatakaFumaria parviflora AUCT. NON. LAM.

This drug is mentioned as the prime remedy of fever in Ayurveda. Fumaria has been traditionally used as a laxative and diuretic. This plant is applied in treatment for dermatologic conditions such as eczema. The drug is suggested to be beneficial in hepatobiliary disorders, and also for colic pain.

 Water hyssop, herb of grace, Indian pennywort.ThrayamanaBacopa monnieri (L.) PENNELL

It is used for improving memory. It has powerful antioxidants and it can reduce inflammation. It boosts brain functions and is used in treatment of ADHD. It can be helpful in anxiety and stress.

Himalayan gentianThrayanthiGentiana kurroo ROYLE.

It has anti-bacterial, anti-oxidant, anti-arthritic, anti-inflammatory, analgesic and immune-modulatory properties.

Coco grass, nut grass, purple nutsredgeMustaCyperus rotundus L.

It has marked anti-inflammatory action. It also has anthelmintic, antioxidant and antifungal properties. The drug improves lactation, relieves fever, burning sensation, and excessive thirst. It is also used in treating diarrhoea, dyspepsia and skin diseases.

Indian gentianBhoonimbaSwertia chirata (ROXB. EX. FLEM.) KAR.

It is an important herb used in Ayurveda for the treatment of fever, inflammation, skin diseases, intestinal parasites and diabetes. It has hepato-protective action also. It is used in treatment of piles, ulcers and fevers.

ConessiKalingaHolarrhena antidysentrica. Wall.

It has been used in bleeding piles, diarrhoea, eczema, fever and colic.  It is beneficial in amoebic dysentery and many other gastro-intestinal disorders.

Long pepperKanaPiper longum

It has carminative action and maybe used as appetizer. The fruit and root of Pippali are used in the form of powder to treat fever, diarrhoea, piles, cough, hiccough, asthma, hoarseness of voice, flatulence, colic, vomiting, acid gastritis, oedema, diseases of mouth, eye diseases, diseases of semen, diseases of women, jaundice, and earache.

 Pippali mixed with honey alleviates cough, dyspnoea, fever splenomegaly, and hiccough.

Red sandalwoodRaktachandanaPterocarpus santalinus L.

It has anti-inflammatory, anti-pyretic, anthelmintic, aphrodisiac, anti-hyperglycaemic and diaphoretic properties. It is used in the treatment of fever, haemorrhage and dysentery.

Details of the manufacturing

As already discussed, Thikthakam ghrutham has 14 ingredients in total

All these ingredients should be washed well and dried up in shade.

For preparation of ghrithakalpana,

We use

  1. Snehadravya (Cow’s ghee)          – 12 Pala 
  • Kashayadravya (For decoction, 1 Pala each)









  • Kalkadravya (For making paste, 1 Karsha each)







Take the prescribed herbs for decoction in dried & crushed form in an earthen pot. Now add 4 times clean water into it. Make it boil and then cook in the open vessel with low fire. Reduce the quantity into one by fourth of the initial quantity. Make sure to mix it in between with a ladle. Also, the fire should be kept low to make sure that all the active ingredients in the herbs needed are absorbed well into the water. Once the quantity is reduced to one by fourth of the initial amount of water, remove the vessel from the fire. Squeeze and drain through a clean white cloth. Collect the decoction in a clean vessel and discard the solid waste.  To this decoction, add the Kalka (paste form of drugs) and continue cooking it in low fire. To this, add cow’s ghee and continue cooking. Stir in between. Check the Paaka as per Snehapakavidhi. Once the desired Paaka is attained, filter the ghruta and keep it in air tight glass bottles after cooling. Ghrutha can be used for a longer period of time without any preservatives.

Dosha Dooshya Predominance with roga marga.

Thikthakam ghrutham is Pitta-Kapha hara.

It acts on aabhyantara, madhyama and bahya rogamarga

Dosage and Usage of Thikthakam ghrutha

Dosage: Generally, it is prescribed in OP practise as 5-15ml once a day.

It is said in text as one Pala or 48 gm in a person with profound digestive fire.

 It differs for Acchasnehapanasodhana) and vicharanasneha(samana)  


Ghrutham is advised to take in empty stomach, once the ingested food is digested well and when the person is having good appetite.

Usage of ghrutham with prescribed prakshepadravyas according to the condition of disease and the patient gives the best results mostly.

Exercises and Yoga.

As Thikthakam ghrutham targets mainly infections, swelling, and immunity, only mild exercises are advised. But when this combination is used for psychotic disorders, relaxing & cooling exercises and meditation are advised. Also, specific Yogacharya including nadisuddhi pranayama, suryanamaskara, bhujangaasana, is recommended.

Regular exercise helps improve the bioavailability of medicine and food ingested and leads to positive health.

 Yoga can maintain harmony within the body and with the surrounding system.

Nadisudhi pranayama



Simple exercises for lungs and heart health

All the exercises and physical exertions must be decided and done under the supervision of a medical expert only.

Recommended diet and behaviour


  • To be avoided

Heavy meals and difficult to digest foods – cause indigestion.

 junk foods- cause a disturbance in digestion and reduces the bioavailability of the medicine

 carbonated drinks – makes the stomach more acidic and disturbed digestion

refrigerated and frozen foods – causes weak and sluggish digestion by weakening Agni (digestive fire)

Milk and milk products – increase Kapha and cause respiratory problems

 curd – causes vidaaha and thereby many other diseases

  • To be added

Light meals and easily digestible foods

Green gram, soups, honey, fruits and vegetables, dry fruits and nuts in moderate quantity.

 freshly cooked and warm food processed with cumin seeds, ginger, black pepper, ajwain, etc


Protect yourself from too much heat.

Better to avoid exposure to excessive sunlight, wind, rain, or dust.

Maintain a regular food and sleep schedule.

Avoid stress.

Avoid sedentary lifestyle. Be active.

Avoid holding or forcing urges like urine, faeces, cough, sneeze, etc.

Avoid sleeping late night.

Side effects and contraindications

No known side effects reported.

Classical references


Equivalent medicines.

Mahathikthakam ghrutham

Brands Available

AVS Kottakal

Vaidyaratnam oushadhasala

AVP Coimbatore

Nagarjuna Ayurveda

Research papers

Patola -an overview


Study in Non-alcoholic fatty liver





Therapeutic roles


These statements have not been evaluated by the Food and Drug Administration, United States. This product is not intended to diagnose, treat, cure or prevent any disease. Please consult your GP before the intake.

Please consult Dr. Rajesh Nair here-


Dr. Rajesh Nair Consultant, Ayurveda Medicine, India

Dr. Rajesh Nair, the co-founder and chief consultant of Ayurvedaforall.Com, is a graduate of prestigious Vaidyaratnam Ayurveda College (affiliated with the University of Calicut), Kerala, India. Additionally, he holds a Postgraduate Diploma in Yoga Therapy from Annamalai University.

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