NIMBAMRUTHADI PANCHATIKTAKAM KASHAYAM- Benefits, Ingredients, Indications, Dosage, Usage, Preparation, Side effects, Equivalent Medicines, Research Papers

Nimbamruthadi panchatiktakam kashayam is an Ayurvedic medicine for a wide array of diseases from skin diseases to liver diseases. It cures many kinds of inflammations in the body.

Benefits of Nimbamruthadi panchatiktakam kashayam

Many skin diseases like psoriasis, atopic dermatitis, heat rash, acne, nail bed infections etc where redness, swelling and burning sensation are present gets cured with this medicine.

 It is beneficial in conditions like inflammation of joints with redness, swelling and fever. It cures fever associated with Pitta-kapha dominance.

 In rheumatoid arthritis it is used to heal the inflammation and improve the function of the affected joints. It acts as a blood purifier.

 It is beneficial in cases of varicose veins with skin rashes.

Ii is used to treat many types of hepatitis. It works as a hepato-protective formulation.

It is used to reduce cysts, abscess and swelling in visceral organs.

Indications of Nimbamruthadi panchatiktakam kashayam

Kushtha              – All types of inflammatory skin diseases

Ingredients of Nimbamruthadi panchatiktakam kashayam

Margosa, NeemNimbaAzadirachta indica A. JUSS.  

The important health benefits of this drug include its ability to treat dandruff, soothe irritation, protect the skin, boost the immune system, and reduce inflammation. It also speeds up wound healing, treats gastric conditions, slows the aging process, improves hair and scalp health, maintains sexual organ health, has anti-cancer potential, and helps treat diabetes.

Heart leaved moonseedAmrutaTinospora cordifolia (WILLD.) HOOK.F. & THOMS

It is effective anti-ulcer drug in action. It is a well-known anti-oxidant and has significant anti-inflammatory property.

Adathoda, Malabar nutVrishaJusticia adathoda L.

It is an expectorant and is mostly used in respiratory conditions. It helps in treatment of skin diseases. It is also used in jaundice, fevers, headache and urinary infections.

Pointed gourdPatolaTrichosanthes dioica Roxb.

It has ant-diabetic, hepato-protective, anti-inflammatory, anti-bacterial, anti-fungal, and wound-healing properties. It has anti-oxidants. It is useful in lowering cholesterol and skin diseases. It acts as a laxative.

Yellow-berried nightshadeNidigdhikaSolanum xanthocarpum

It has anti-oxidant and anti-cancer activities. It possesses anti-asthmatic, hypoglycaemic, hepatoprotective, anti-bacterial and insect repellent properties.

Details of the manufacturing

Nimbamruthadi panchatiktakam kashayam has 5 ingredients. Six of them are taken in equal quantity.

All these ingredients should be washed well and dried up in shade.

Take the prescribed herbs in dried & crushed form in an earthen pot. Now add 16 times water into it. Make it boil and then cook in the open vessel with low fire. Reduce the quantity into one by eighth of the initial quantity. Make sure to mix it in between with a wooden spatula. Also, the fire should be kept low to make sure that all the active ingredients in the herbs needed are absorbed well into the water. Once the quantity is reduced to one by eighth of the initial amount of water, remove the vessel from the fire. Squeeze and drain through a clean white cloth. Collect the decoction in a clean vessel and discard the solid waste. Drink the mild warm decoction.

Dosha Dooshya Predominance with roga margas.

Nimbamruthadi panchatiktakam kashayam is Pitta-Kaphahara.

It acts on bahir-rogamarga.

Dosage and Usage of Nimbamruthadi panchatiktakam kashayam

Dosage: two Pala.

Usage:

Kashayam is advised to take in empty stomach, once the ingested food is digested well and aahaararasa is formed well.

Usage of kashayam with prescribed prakshepadravyas according to the condition of disease and the patient gives the best results mostly.

Exercises and Yoga.

Nimbamruthadi panchatiktakam kashayam is used mainly in skin diseases. Sweating is the best way to cleanse the skin. While it is used in skin diseases with joint inflammation, vigorous exercises are not allowed in painful conditions.

 Only stretching, moderate walking, and mild cardio exercises are advised. Also, specific yogacharya including bhujangaasana, salabhasana, vajrasana is recommended. Range of movement and flexibility must be considered while doing every exercise. 

Sookshma sandhi vyayama (warming up small joints) is advised.

Regular exercise helps improve bioavailability of the medicine and food ingested and leads to positive health.

 Yoga can maintain harmony within the body and with the surrounding system.

Salabhasana

vajrasana

Bhujangasana

All the exercises and physical exertions must be decided and done under the supervision of a medical expert only.

Recommended diet and behaviour

Diet:

  • To be avoided

Heavy meals and difficult to digest foods – cause indigestion.

 junk foods- cause disturbance in digestion and reduces the bioavailability of the medicine

 carbonated drinks – makes the stomach more acidic and disturbed digestion

refrigerated and frozen foods – causes weak and sluggish digestion by weakening Agni (digestive fire)

curd – causes vidaaha and thereby many other diseases

Red chili and other pungent, hot and spicy food items.

Excess intake of salt.

  • To be added

Light meals and easily digestible foods

Green gram, soups, fruits and vegetables.

 freshly cooked and warm food processed with cumin seeds, ginger, ajwain etc

Behaviour:

Better to avoid exposure to excessive sunlight wind rain or dust.

Avoid sedentary lifestyle as it is one of the main causes of rheumatoid arthritis.

Maintain a regular food and sleep schedule.

Avoid holding or forcing the urges like urine, faeces, cough, sneeze etc.

Side effects and contraindications

No known side effects reported.

In persons with a sensitive stomach, it may cause abdominal discomforts and diarrhoea.

Classical reference

ASHTANGAHRUDYA CHIKITSASTHANA 21/58-61

Equivalent medicines.

Patolakaturohinyadi kashayam

Guduchyadi kashayam

Brands Available

Research papers

Patola -an overview

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358970/

Nidigdhika

antimicrobial

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6948065/

Nimba

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3695574/

GUDUCHI

ANTI OXIDANT AND ANTI INFLAMMATORY

The objective of the present work is to study the antioxidant and anti-inflammatory effect of alcoholic and water extracts of T. cordifolia (Willd.) Miers leaves in activated human monocytic THP-1 cells.

T. cordifolia (Willd.) Miers extracts exhibited significant amounts of total phenolic and flavonoid content, and LC-MS/MS analyses detected tinosponone, a TC-specific clerodane-derived diterpene. Both types of extracts attenuated AA-induced ROS generation via enhancing catalase enzyme activity in THP-1 cells. Real time PCR and ELISA experiments revealed that the elevated levels of LPS-induced TNF-α was remarkably attenuated in THP-1 cells pretreated with T. cordifolia (Willd.) Miers extracts. Western blot and confocal microscopy showed that the alcoholic extract’s anti-inflammatory activity by attenuating NF-κB translocation into the nucleus in LPS-activated THP-1 cells via the inhibition of IκB degradation in the cytosol.

The findings suggest that T. cordifolia (Willd.) Miers dry leaf extracts possess antioxidant and anti-inflammatory properties via upregulation of antioxidant enzymes and attenuation of NF- κB nuclear translocation in activated human monocytic (THP-1) cells.

doi: 10.1016/j.phymed.2019.152831.

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